Yukon Choice PC®
Sirolinus Eluting Coronary Stent System
New generation DES providing synergy of Biodegradable Polymer with microporous surface to enhance optimal performance
One million pores per cm2 with an average depth of 2 µm ensures optimum drug release with minimal use of polymer
Top coat with Shellac Resin ensures better polymer- drug binding with negligible polymer flaking during stent expansion
Drug and polymer are co-released in 6-9 months leaving behind bare metal stent surface
Drug polymer matrix coated only on the abluminal side using patented stent coating technology for drug release only to target tissue
No polymer on the luminal side ensures healthy endothelialisation and reduces the incidence of stent thrombosis
World's Longest Studied Drug Eluting Stent
In this long term analysis at 10 years showed that is equivalent to PP-EES in Diabetic Patients
At 10 years, Yukon Choice PC showed equivalence in terms of MACE rate, Mortality and TLR rate compared to Xience and a superiority over Cypher for the same outcomes.
Yukon Choice PC showed the lowest rate of definite or probable stent thrombosis with a significant risk reduction than the Cypher stent (50% reduction) and a numerically lower rate as than the ‘Xience’ stent (29% reduction).
Yukon Choice PC is recommended by ESC guidelines 2018 on the basis of large randomized trials where primary end points were achieved.
Yukon Choice PC showed equivalent efficacy & better safety in terms of stent thrombosis compared to Xience & Cypher at 5 years follow up.
At four years follow up, Yukon Choice PC demonstrated reduced rates in stent thrombosis in patients with diabetes mellitus as compared to durable polymer.
At four years follow up, Yukon Choice PC shows reduction of risk by 50% in Definite Stent Thrombosis & by 78% in Very Late stent thrombosis as compared to the first generation DES with similar efficacy.
At 3 years, Yukon Choice PC proved equivalance to Xience in terms of Late loss, TLR and Primary Composite MACE.
In Pre-clinical trial, it was seen that Yukon Choice PC with microporous surface reduced the amount of polymeric load to 1/4th and is assured with consistent kinetics & low inflammation.
At 2 years, microporous surface was found to be equally safe as compared to electropolished surface. Rough surfaces showed lesser restenosis rates.